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1

Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor

Zaiss, Dietmar M.W., van Loosdregt, Jorg, Gorlani, Andrea, Bekker, Cornelis P.J., Gröne, Andrea, Sibilia, Maria, van Bergen en Henegouwen, Paul M.P., Roovers, Rob C., Coffer, Paul J., Sijts, Alice J.A

Journal:

Year:

2013

Language:

english

File:

PDF, 875 KB

english, 2013

2

Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

van Loosdregt, Jorg, Fleskens, Veerle, Fu, Juan, Brenkman, Arjan B., Bekker, Cornelis P.J., Pals, Cornelieke E.G.M., Meerding, Jenny, Berkers, Celia R., Barbi, Joseph, Gröne, Andrea, Sijts, Alice J.A.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.40 MB

english, 2013

3

Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function

van Loosdregt, Jorg, Fleskens, Veerle, Tiemessen, Machteld M., Mokry, Michal, van Boxtel, Ruben, Meerding, Jenny, Pals, Cornelieke E.G.M., Kurek, Dorota, Baert, Miranda R.M., Delemarre, Eveline M., Gr

Journal:

Year:

2013

Language:

english

File:

PDF, 2.15 MB

english, 2013

4

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: A possible mechanism for therapeutic modulation of T cells

van Loosdregt, Jorg, Spreafico, Roberto, Rossetti, Maura, Prakken, Berent J., Lotz, Martin, Albani, Salvatore

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 280 KB

english, 2013

5

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60

Gao, Yuan, Koppen, Arjen, Rakhshandehroo, Maryam, Tasdelen, Ismayil, van de Graaf, Stan F., van Loosdregt, Jorg, van Beekum, Olivier, Hamers, Nicole, van Leenen, Dik, Berkers, Celia R., Berger, Ruud,

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

6

Post-translational modification networks regulating FOXP3 function

van Loosdregt, Jorg, Coffer, Paul J.

Journal:

Trends in Immunology

Year:

2014

Language:

english

File:

PDF, 660 KB

english, 2014

7

A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples

Spreafico, Roberto, Rossetti, Maura, van den Broek, Theo, Jansen, Nicolaas J.G., Zhang, Hong, Moshref, Maryam, Prakken, Berent, van Loosdregt, Jorg, van Wijk, Femke, Albani, Salvatore

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 401 KB

english, 2014

8

Increased autophagy in CD4 + T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance

Loosdregt, Jorg, Rossetti, Maura, Spreafico, Roberto, Moshref, Maryam, Olmer, Merissa, Williams, Gary W., Venkatanarayanan, Hari Balaji, Kumar, Pavanish, Copeland, Dana, Pischel, Ken, Lotz, Martin, Al

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.54 MB

english, 2016

9

Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells

Peeters, Janneke G. C., de Graeff, Nienke, Lotz, Martin, Albani, Salvatore, de Roock, Sytze, van Loosdregt, Jorg

Journal:

Year:

2017

Language:

english

File:

PDF, 605 KB

english, 2017

10

Enhancers in autoimmune arthritis: Implications and therapeutic potential

Peeters, Janneke G.C., Vastert, Sebastiaan J., van Wijk, Femke, van Loosdregt, Jorg

Journal:

Arthritis & Rheumatology

Year:

2017

Language:

english

File:

PDF, 977 KB

english, 2017

11

Update on research and clinical translation on specific clinical areas from biology to bedside: Unpacking the mysteries of juvenile idiopathic arthritis pathogenesis

van Loosdregt, Jorg, van Wijk, Femke, Prakken, Berent, Vastert, Bas

Journal:

Best Practice & Research Clinical Rheumatology

Year:

2018

Language:

english

File:

PDF, 499 KB

english, 2018

12

Molecular mechanisms of autophagic memory in pathogenic T cells in human arthritis

Kumar, Pavanish, Yao, Leong Jing, Saidin, Suzan, Paleja, Bhairav, van Loosdregt, Jorg, Chua, Camillus, Arkachaisri, Thaschawee, Consolaro, Alessandro, Gattorno, Marco, Martini, Alberto, Pischel, Ken D

Journal:

Journal of Autoimmunity

Year:

2018

Language:

english

File:

PDF, 2.28 MB

english, 2018

13

Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method: a study protocol

Schoemaker, Casper G., Armbrust, Wineke, Swart, Joost F., Vastert, Sebastiaan J., van Loosdregt, Jorg, Verwoerd, Anouk, Whiting, Caroline, Cowan, Katherine, Olsder, Wendy, Versluis, Els, van Vliet, Re

Journal:

Pediatric Rheumatology

Year:

2018

Language:

english

File:

PDF, 542 KB

english, 2018

14

The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home

van Loosdregt, Jorg, Coffer, Paul J.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

15

Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis

Nijhuis, Lotte, Peeters, Janneke G. C., Vastert, Sebastiaan J., van Loosdregt, Jorg

Journal:

Frontiers in Immunology

Year:

2019

Language:

english

File:

PDF, 1.20 MB

english, 2019